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Farhad Sahebjam,John M. Vierling
Frontiers of Medicine 2015, Volume 9, Issue 2, Pages 187-219 doi: 10.1007/s11684-015-0386-y
Autoimmune hepatitis is a chronic liver disease putatively caused by loss of tolerance to hepatocyte-specificSince many features also occur in other chronic liver diseases, these scoring systems aid evaluationLiver transplantation represents a life-saving option for patients presenting with acute liver failure
Keywords: autoimmune hepatitis autoantibodies diagnosis immunological diseases drug-induced liver injury therapy immunosuppression outcomes hepatocellular carcinoma liver transplantation
Clinical analysis of 275 cases of acute drug-induced liver disease
LI Lei, JIANG Wei, WANG Jiyao
Frontiers of Medicine 2007, Volume 1, Issue 1, Pages 58-61 doi: 10.1007/s11684-007-0012-8
Bavachin enhances NLRP3 inflammasome activation induced by ATP or nigericin and causes idiosyncratic
Nan Qin, Guang Xu, Yan Wang, Xiaoyan Zhan, Yuan Gao, Zhilei Wang, Shubin Fu, Wei Shi, Xiaorong Hou, Chunyu Wang, Ruisheng Li, Yan Liu, Jiabo Wang, Haiping Zhao, Xiaohe Xiao, Zhaofang Bai
Frontiers of Medicine 2021, Volume 15, Issue 4, Pages 594-607 doi: 10.1007/s11684-020-0809-2
Keywords: Psoraleae Fructus bavachin idiosyncratic drug-induced liver injury caspase-1 IL-1β NLRP3 inflammasome
Jiabo Wang,Zhijie Ma,Ming Niu,Yun Zhu,Qingsheng Liang,Yanling Zhao,Jingyuan Song,Zhaofang Bai,Yaming Zhang,Ping Zhang,Na Li,Yakun Meng,Qi Li,Lushan Qin,Guangju Teng,Junling Cao,Baosen Li,Shilin Chen,Yonggang Li,Zhengsheng Zou,Honghao Zhou,Xiaohe Xiao
Frontiers of Medicine 2015, Volume 9, Issue 4, Pages 457-467 doi: 10.1007/s11684-015-0417-8
Herbal medicines have recently been recognized as the second most common cause of drug-induced liverinjury (DILI) in the United States.In this study, a total of 12 307 inpatients with liver dysfunction and 147 literature-reported cases
Keywords: drug-induced liver injury pharmacognosy metabolomics stilbene Polygonum multiflorum Chinese herbal
Xiaofang Cui, Benting Ma, Yan Wang, Yan Chen, Chunling Shen, Ying Kuang, Jian Fei, Lungen Lu, Zhugang Wang
Frontiers of Medicine 2019, Volume 13, Issue 1, Pages 104-111 doi: 10.1007/s11684-017-0568-x
Keywords: retinol dehydrogenase 13 carbon tetrachloride acute liver injury Cyp2e1 Spot14
Leonurine protects ischemia-induced brain injury via modulating SOD, MDA and GABA levels
Shilei ZHENG, Jingru ZHU, Jiao LI, Shuang ZHANG, Yunfei MA
Frontiers of Agricultural Science and Engineering 2019, Volume 6, Issue 2, Pages 197-205 doi: 10.15302/J-FASE-2018245
Keywords: cerebral ischemia GABA neuroprotection leonurine SOD
Wu Limao,Li Lianda,Liu Hong,Ning Keyong,Li Yikui
Strategic Study of CAE 2004, Volume 6, Issue 7, Pages 34-42
Keywords: bone marrow stem cells autologous transplantation liver injury liver fibrosis guiyuan fang
Rui ZHU MD , Lin SHEN MD , Jianguo LIU MD , Weili ZHANG MM , Ling YANG MD ,
Frontiers of Medicine 2009, Volume 3, Issue 3, Pages 363-367 doi: 10.1007/s11684-009-0064-z
Keywords: liver disease alcohol Zhihuang decoction CD14 signal transduction
Glucagon-like peptide-2 exhibits protective effect on hepatic ischemia-reperfusion injury in rats
Naci Topaloğlu,Adem Küçük,Şule Yıldırım,Mustafa Tekin,Havva Erdem,Mustafa Deniz
Frontiers of Medicine 2015, Volume 9, Issue 3, Pages 368-373 doi: 10.1007/s11684-015-0403-1
Keywords: ischemia/reperfusion liver glucagon-like peptide-2 alanine aminotransferase
Qiusha Pan, Peifang Song, Zhenhua Ni, Xingkai Qian, Anqi Wang, Liwei Zou, Yong Liu, Ping Wang, Weidong Zhang, Hong Ma, Ling Yang
Engineering 2022, Volume 19, Issue 12, Pages 153-165 doi: 10.1016/j.eng.2021.09.014
Accurately assessing and tracking the progression of liver-specific injury remains a major challengeinjury.We found that both QFPDD and UDCA attenuated ANIT-induced liver damage.injury–an application that allows for the differentiation of liver damage and inflammatory liverinjury.
Keywords: Carboxylesterase 1 Dipeptidyl peptidase 4 Liver injury Validation tracking
Frontiers of Medicine 2022, Volume 16, Issue 1, Pages 111-125 doi: 10.1007/s11684-021-0854-5
Keywords: COVID-19 chronic hepatitis B liver injury coagulation dysfunction
Chunyu Li, Ming Niu, Zhaofang Bai, Congen Zhang, Yanling Zhao, Ruiyu Li, Can Tu, Huifang Li, Jing Jing, Yakun Meng, Zhijie Ma, Wuwen Feng, Jinfa Tang, Yun Zhu, Jinjie Li, Xiaoya Shang, Zhengsheng Zou, Xiaohe Xiao, Jiabo Wang
Frontiers of Medicine 2017, Volume 11, Issue 2, Pages 253-265 doi: 10.1007/s11684-017-0508-9
Keywords: Polygonum multiflorum idiosyncratic hepatotoxicity metabolomics stilbene cis-transisomerization
Yang An, Chao Chen, Jundong Zhu, Pankaj Dwivedi, Yanjun Zhao, Zheng Wang
Frontiers of Chemical Science and Engineering 2020, Volume 14, Issue 5, Pages 880-888 doi: 10.1007/s11705-019-1864-6
Keywords: hypoxia microtubule inhibitor drug delivery azo-combretastatin A4 photo-responsive
Bile duct injury repair — earlier is not better
Vinay K. Kapoor
Frontiers of Medicine 2015, Volume 9, Issue 4, Pages 508-511 doi: 10.1007/s11684-015-0418-7
Bile duct injury is a common complication of cholecystectomy.The timing of bile duct injury repair remains controversial.Most patients with bile duct injury present with bile leak and sepsis; thus, early repair is not recommendedendoscopic stenting are the mainstays of treatment of bile leak because they convert acute bile duct injury
Keywords: bile duct injury cholecystectomy laparoscopic cholecystectomy
Yanli LIU, Rong LIU, Cheng ZHEN, Quanfang GUO, Liping WU, Zhaoxi DING, Yushun BI, Zhiyu LIU
Frontiers of Medicine 2009, Volume 3, Issue 1, Pages 91-95 doi: 10.1007/s11684-009-0011-z
Keywords: Fuganling granula immunological liver injury bacille calmette guerin lipopolysaccharide mice
Title Author Date Type Operation
Clinical analysis of 275 cases of acute drug-induced liver disease
LI Lei, JIANG Wei, WANG Jiyao
Journal Article
Bavachin enhances NLRP3 inflammasome activation induced by ATP or nigericin and causes idiosyncratic
Nan Qin, Guang Xu, Yan Wang, Xiaoyan Zhan, Yuan Gao, Zhilei Wang, Shubin Fu, Wei Shi, Xiaorong Hou, Chunyu Wang, Ruisheng Li, Yan Liu, Jiabo Wang, Haiping Zhao, Xiaohe Xiao, Zhaofang Bai
Journal Article
Evidence chain-based causality identification in herb-induced liver injury: exemplification of a well-knownliver-restorative herb
Jiabo Wang,Zhijie Ma,Ming Niu,Yun Zhu,Qingsheng Liang,Yanling Zhao,Jingyuan Song,Zhaofang Bai,Yaming Zhang,Ping Zhang,Na Li,Yakun Meng,Qi Li,Lushan Qin,Guangju Teng,Junling Cao,Baosen Li,Shilin Chen,Yonggang Li,Zhengsheng Zou,Honghao Zhou,Xiaohe Xiao
Journal Article
Rdh13 deficiency weakens carbon tetrachloride-induced liver injury by regulating Spot14 and Cyp2e1 expression
Xiaofang Cui, Benting Ma, Yan Wang, Yan Chen, Chunling Shen, Ying Kuang, Jian Fei, Lungen Lu, Zhugang Wang
Journal Article
Leonurine protects ischemia-induced brain injury via modulating SOD, MDA and GABA levels
Shilei ZHENG, Jingru ZHU, Jiao LI, Shuang ZHANG, Yunfei MA
Journal Article
Studies of the Guiyuan Fang and Autologous Bone Marrow Stem Cells Transplantation on Hepatic Injury and
Wu Limao,Li Lianda,Liu Hong,Ning Keyong,Li Yikui
Journal Article
Effect of decoction on CD14 expression in lipopolysaccharide signal transduction pathway of alcohol-inducedliver disease in rats
Rui ZHU MD , Lin SHEN MD , Jianguo LIU MD , Weili ZHANG MM , Ling YANG MD ,
Journal Article
Glucagon-like peptide-2 exhibits protective effect on hepatic ischemia-reperfusion injury in rats
Naci Topaloğlu,Adem Küçük,Şule Yıldırım,Mustafa Tekin,Havva Erdem,Mustafa Deniz
Journal Article
Accurate Assessment and Tracking the Process of Liver-Specific Injury by the Residual Tissue Activity
Qiusha Pan, Peifang Song, Zhenhua Ni, Xingkai Qian, Anqi Wang, Liwei Zou, Yong Liu, Ping Wang, Weidong Zhang, Hong Ma, Ling Yang
Journal Article
Clinical characteristics and risk factors of COVID-19 patients with chronic hepatitis B: a multi-center retrospective cohort study
Journal Article
Screening for main components associated with the idiosyncratic hepatotoxicity of a tonic herb, Polygonum
Chunyu Li, Ming Niu, Zhaofang Bai, Congen Zhang, Yanling Zhao, Ruiyu Li, Can Tu, Huifang Li, Jing Jing, Yakun Meng, Zhijie Ma, Wuwen Feng, Jinfa Tang, Yun Zhu, Jinjie Li, Xiaoya Shang, Zhengsheng Zou, Xiaohe Xiao, Jiabo Wang
Journal Article
Hypoxia-induced activity loss of a photo-responsive microtubule inhibitor azobenzene combretastatin A4
Yang An, Chao Chen, Jundong Zhu, Pankaj Dwivedi, Yanjun Zhao, Zheng Wang
Journal Article